Resolving the shape and mechanics of biomolecules — from single proteins to macromolecular assemblies — to understand how structure gives rise to function.
Researchers here combine biomolecular NMR, X-ray and spectroscopic methods with live-cell biophysics to connect molecular structure to cellular function. Themes include membrane and cortical mechanics, protein folding and self-assembly, structural proteomics of clinically relevant molecules, and the biophysics of macromolecular interactions — supported by the department's Bio-Analytical Facility and Central Imaging Facility.
